Clinical Obesity Genetics

Part 1: Introduction.- General introduction to obesity genetics and genomics.- General introduction obesity in children and adults.- Part 2: Clinical disorders.- Prader-Willi syndrome.- Chung-Jansen syndrome (PHIP-related disorder).- 16p11.2 16p11.2 deletion syndrome.- Schaaf-Yang syndrome (MAGEL2).- Bardet-Biedl syndrome.- Pseudohypoparathyroidism and its association with obesity.- Non-syndromic Leptin melanocortin pathway disorders.- Leptin and Leptin receptor deficiency.- POMC deficiency.- MC4R deficiency.- Part 3: Genetic analysis?- PCSK1 deficiency.- Methylation analysis in diagnostics; the episignature.- Part 4: Clinical treatment.- Anti-obesity pharmacotherapy for patients with genetic obesity disorders.- Metabolic Bariatric surgery.- Part 5: Future directions.- Circadian clock genes.- Functional assessment of G-protein coupled receptor variants associated with genetic obesity.- DNA medication pass: If genomics data is available, why not look at pharmacogenetic variants too?.- Genome-wide association studies and poligenic risk prediction in obesity research.

• Erscheinungsdatum: 01.01.2026
• Autor/Autorin: Mieke van Haelst
• Reihe: Medicine (R0)
• Format: E-Book
• Dateiformat: PDF
• Kopierschutz: Wasserzeichen
• Dateigröße: 11.2 MB
• Verlag: SPRINGER
• Sprache: Englisch
• Umfang: 246 Seiten
• ISBN: 9783032040954
• Lieferung: Sofort per Download
• Hinweis: Sofort per Download lieferbar. Kein physischer Versand.
• Kompatibilität: Lesbar auf Geräten und Apps mit PDF-Unterstützung.