Blood Substitutes and Oxygen Biotherapeutics

Biochemistry of Hemoglobin and Hemoglobin-Based Oxygen Carrier.- Platelet Mimicry for Biomechanical Function.- HBOC Impact Upon Vasoactive Effectors, Rheology and Blood Flow.- Recombinant Hemoglobins with Enhanced Oxydative Stability.- Nitric Oxide Protectants as a Potential Adjunct of HBOCs.- Non-hemoglobin Engineered Protein Oxygen Carriers: Omniox.- Metal-Organic Framework-Based Oxygen Carriers.- Coupled Cross-Linked Human Hemoglobins (Bis-Tetramers) Overcome HBOC Problems.- Hemoglobin-based Oxygen Carriers, Oxidative Stress and Myocardial Infarction – Issues and Implications for HBOC Development.- Fractionated Polymerized Hemoglobin-A Modernized Erythrocytic Substitute and Oxygen Biotherapeutic.- Hemoglobin-Based Oxygen Carriers: Toxicity Mechanisms and Molecular Mitigation Strategies.- Nitric Oxide and Hemoglobin: physiological implications.- Ideal P50: The Ability to Design Artificial Oxygen Carriers and to Create a Product that Self Regulates.- Hemoglobin-Based Oxygen Carriers: Evolving Concepts and Clinical Implications.- HBOC Design Using Protein Engineering.- Pegylated Bovine Hemoglobin: Manufacturing and Characterization.- Benefits and risks of encapsulated Hb as an artificial oxygen carrier.- Cardiovascular Effects of Hemoglobin-Based Oxygen Carriers.- Perfluorocarbon-based Oxygen Carriers: A Comprehensive Overview.- Expanded Access when Blood Not an Option: Use of Hemopure and Sanguinate.- Perfluorocarbon-based artificial oxygen carriers for kidney and heart perfusion.- Perfluorocarbon-based Artificial Oxygen Carriers for Ex Vivo Organ Perfusion.- The Erythrocruorins as Synthetic Blood Products: What Is New?.- Whole Blood vs Blood Component Therapy.- Biosynthetic Blood Components: Use Case for Hemorrhagic Shock and Clinical Trial Design.- Phase I clinical trial of hemoglobin vesicles (HbV).- Blinded, Randomized, Controlled Trials of HBOC-201 (Hemopure).- Clinical Development and Therapeutic Applications of Clinical Development and Therapeutic Applications of SANGUINATE (PP-007).- Real-Time Circulating Blood Volume Measurements Using Hemoglobin-based Oxygen Carriers: A Novel Alternative to Traditional Methods.- YQ23: A New Hemoglobin Based Oxygen Carrier in Critical Limb Ischemia — Phase I/II Trials.- The Therapeutic Potential of Plasma Extracellular Vesicles.- Pathogen Reduction for Novel Blood Product Development.- Prothrombin Complex Concentrate as a Therapeutic in Trauma.- The Regenerative Properties of Plasma in Burns.- The Role of Cryoprecipitate in Trauma-Induced Hemorrhagic Shock and Endotheliopathy.- Plasma versus Factor Concentrates Therapy.- The Endotheliopathy of Trauma Patients with Plasma Product Transfusion: Emerging Clinical Developments.- Solvent/Detergent-Treated Pooled Plasma Products and Factor Concentrates.- Freeze Dried Plasma.- Platelets-Fibrin-RBC Interactions in Hemostatic Clots.- Apheresis Platelet Product Functional Variability.- SynthoPlate and Related Platelet-Inspired Synthetic Nanotechnologies for Hemorrhage Control.- Blood Substitutes Related Regulatory Updates (FDA/CBER).- Innovative Pre-Clinical Models to Prepare Products for FDA Review.- The Regulatory Challenges of Producing Dried Plasma or What’s a Regulator to Do?.- The addition of a simple aqueous solution of synthetic neocatalase, neosuperoxide dismutase and neocarbonic anhydrase improve the effectiveness of oxygen carriers for the preservation of warm ischemic cell/tissue.- A Military-Civilian Partnership Model to Advance Commercialization of Blood Products.- Acute Safety Study of the Intravenous Injection of a Lyophilized Form of an Extracellular Hemoglobin, M101, in the Rat.

• Erscheinungsdatum: 17.07.2026
• Autor/Autorin: Henry Liu
• Reihe: Medicine (R0)
• Format: E-Book
• Dateiformat: PDF
• Kopierschutz: Wasserzeichen
• Dateigröße: 35.4 MB
• Auflage: Second Edition 2026
• Verlag: SPRINGER
• Sprache: Englisch
• Umfang: 412 Seiten
• ISBN: 9783032226563
• Lieferung: Download ab 17.07.2026
• Hinweis: Vorbestellung. Verfügbar per Download ab Erscheinungstag. Kein physischer Versand.
• Kompatibilität: Lesbar auf Geräten und Apps mit PDF-Unterstützung.

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