{"product_id":"histone-and-non-histone-reversible-acetylation-in-development-aging-and-disease-ebook","title":"Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease","description":"\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0cm; text-align: justify;\"\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eThis volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0cm; text-align: justify;\"\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eIt examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.\u003c\/span\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0cm; text-align: justify;\"\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eThe book is divided in four parts:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\" style=\"text-align: justify;\"\u003e\n\u003c!--[endif]--\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003ePart I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher genome organiz\u003c\/span\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eation and explores the functions of the proteins involved.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"text-align: justify;\"\u003e\n\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003ePart II focuses on the modulation of cytoskeleton-associated proteins through reversible acetylation.\u003c\/span\u003e\u003cspan style=\"text-indent: -18pt;\"\u003e \u003c\/span\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eIt examines how acetylation influences cytoskeletal compartments, thereby regulating cellular structure and function.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"text-align: justify;\"\u003e\n\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003ePart III\u003c\/span\u003e\u003cspan style=\"text-indent: -18pt;\"\u003e \u003c\/span\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eexamines acetylation in the context of development. It describes acetylation as a key regulator of early embryogenesis, influencing chromatin structure and gene expression.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"text-align: justify;\"\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003ePart IV discusses physiological and pathological aspects of histone and non-histone protein acetylation and its modulation by activators and inhibitors.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"mso-bidi-font-family: Calibri; mso-bidi-theme-font: minor-latin;\"\u003eThe book is a valuable resource for scientists, clinicians and academic teachers alike.\u003c\/span\u003e\u003c\/p\u003e","brand":"Marta Halasa","offers":[{"title":"Default Title","offer_id":53652470464839,"sku":"9783031914591","price":213.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/histone-and-non-histone-reversible-acetylation-in--ebook-cover.webp?v=1775366698","url":"https:\/\/www.cinebuch.de\/products\/histone-and-non-histone-reversible-acetylation-in-development-aging-and-disease-ebook","provider":"CineBuch","version":"1.0","type":"link"}