{"title":"Advances in Experimental Medicine and Biology","description":"\u003cp\u003eBücher aus der Reihe: Advances in Experimental Medicine and Biology\u003c\/p\u003e","products":[{"product_id":"reproductive-sciences-in-animal-conservation-ebook","title":"Reproductive Sciences in Animal Conservation","description":"\u003cp\u003e\u003cspan lang=\"EN-US\" style=\"font-size: 11.0pt; line-height: 107%; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\"\u003eForeword.- \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 107%; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-IN; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\"\u003eReproductive sciences to the rescue of wild animal species.- Reproductive strategies and their relevance to vertebrate conservation.- Stress, Well-being, and Reproduction in Wildlife.- Ethical and regulation aspects relevant to the study of reproduction in wild species.- Transgenerational Impact of Environmental Change.- Reproductive impact of natural, synthetic and emerging chemicals on wildlife and domestic animals.- The Potential Roles of Extracellular Vesicles in Wild Animals’ Reproduction.- Molecular tools for non-invasive sexing of wildlife.- Sperm DNA Fragmentation: the concept and its use in assisted reproduction.- Stem Cells and Wildlife Conservation.- Conservation of honeybee (Apis mellifera) intraspecific diversity through reproductive science and technology.- Conservation of teleost fishes: Current status and the role of reproductive technologies.- Reproductive Modes of Amphibians and Reptiles:  Impacts on Conservation and the Development of Assisted Reproductive Technologies.- Wild Bird Reproduction: Neuroendocrinology, Conservation Biology, and Environmental Threats.- The emerging role of prolactin as a biomarker for reproduction, health, and welfare in wildlife species: Elephants as a model.- Koala Conservation: The Utility of Art and Genome Banking.- Reproductive science methods for marine mammals.- Fertility Control in Wildlife: Review of Current Status, Including Novel and Future Technologies.- How to ensure a bright future for reproductive sciences in animal conservation.\u003c\/span\u003e\u003c\/p\u003e","brand":"Pierre Comizzoli","offers":[{"title":"Default Title","offer_id":53627976679751,"sku":"9783031877070","price":192.59,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/reproductive-sciences-in-animal-conservation-ebook.webp?v=1775150255"},{"product_id":"oxygen-transport-to-tissue-xlvi-ebook","title":"Oxygen Transport to Tissue XLVI","description":"\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; background: white;\"\u003e\u003cstrong\u003e\u003cspan lang=\"EN\" style=\"font-size: 10.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Times; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN; font-weight: normal;\"\u003eRole of mitochondrial optical redox imaging in modern cancer research.- Mind the individual physiological reactions to long term colored light exposure assessed by SPA.- A novel approach to \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cem style=\"mso-bidi-font-style: normal;\"\u003e\u003cspan style=\"font-size: 10.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Times; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; font-weight: normal; mso-bidi-font-weight: bold;\"\u003ein vivo\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN\" style=\"font-size: 10.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Times; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN; font-weight: normal;\"\u003e EPR spectroscopy for repeatable assessments of oxygenation levels in tumors at any depth preliminary feasibility studies utilizing a multisite oxygen sensor inside HDR brachytherapy needles.- What is the information content of EPR oximetry.- Letting biology validate the EPR imaging of tumor.- Random acquisition of spectral projections in four dimensional spectral spatial EPR imaging a feasibility study toward oxygen imaging.- A portable broadband near infrared spectroscopy device for \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cem style=\"mso-bidi-font-style: normal;\"\u003e\u003cspan style=\"font-size: 10.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Times; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; font-weight: normal; mso-bidi-font-weight: bold;\"\u003ein vivo\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN\" style=\"font-size: 10.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Times; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN; font-weight: normal;\"\u003e oxygenation and metabolism measurements.- Non contact oxygenation assessment of biological tissues based on a time of flight method.- Dependence of reflectance on optical properties at short distance.- Dependence of reflectance on optical properties at short distance.- Influence of breast tumor associated lipids on oxygen transport across model cell membranes.- Simulating gas permeation through the central pore of AQP5.- Role of the dual specificity phosphatase signaling by hypoxia or acidosis in tumor cells.- Blood flow regulates metabolism in hematopoietic development.- Erythrocytes as active regulators of blood flow a brief overview.- Capillary red blood cell velocity is decreased in skeletal muscle of septic rats in vivo imaging using videocapillaroscopy.- The role of nitric oxide in regulating microvascular oxygen pressure during diaphragm contraction in rats.- Influence of arterial occlusion at various cuff positions on systemic circulation measured by remote photoplethymography.- Physiological effects of photobiomodulation therapy in the treatment of multiple concussions.- Photobiomodulation increases eye movement conjugation in healthy volunteers.- Brain synchronization when sharing positive emotions based on memories hyperscanning study.- Unlocking unique physiological reactions novel insights into four cerebral and systemic physiological responses to colored light.- Long term modulation of brain tissue oxygenation and electrophysiological activity following neonatal anesthesia exposure.- Unravelling the connection between reduced mobility and mild cognitive impairment in chronic pain patients through cluster analysis.- Time dependent efficacy of drag reducing polymers in the treatment of permanent middle cerebral artery occlusion injury in rats.- Prefrontal cortex oxygenation dynamics during walking in patients with acute stroke.- Cerebral edema depends on the results of large vascular occlusion reperfusion therapy.- Net water uptake and cerebral microcirculation in perilesional penumbra in TBI CT perfusion study.- Uncontrolled orthostatic hypotension and multi channel cerebral hemodynamic changes in a young male participant a case report.- Dynamic changes in cerebral oxygenation and arterial pressure during repeated rapid hypotension.- Patients admitted to the ICU who cannot be mobilized for the first time within hours have low regional cerebral oxygen saturation.- derived muscle deoxygenation during arterial occlusion at rest before and after body weight resistance training with slow movement and tonic force generation.- Characteristics of muscle oxygenation of the upper and lower limb during moderate intensity upper limb crank exercise a near infrared spectroscopy study.- Compensatory oxygenation changes in non active and active muscles during incremental exercise in healthy adults.- Pulse oximeters accuracy and artifacts.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Sally C. Pias","offers":[{"title":"Default Title","offer_id":53628087566663,"sku":"9783032103895","price":266.43,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/oxygen-transport-to-tissue-xlvi-ebook.webp?v=1775015293"},{"product_id":"the-drosophila-model-in-cancer-ebook","title":"The Drosophila Model in Cancer","description":"\u003cp class=\"xxmsonormal\" style=\"margin: 0cm; margin-bottom: .0001pt; line-height: 13.8pt; background: white;\"\u003eChapter 1. Unveiling the Tumor Suppressors: Insights from Drosophila.- Chapter 2. Notch signaling in Drosophila tumor models.- Chapter 3. Non-autonomous Regulation of Tumor Growth.- Chapter 4. Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues. - Chapter 5. The power of Drosophila in Modeling Cancer Cachexia.- Chapter 6. Drosophila Intestine as a Model to Study Tumors.- Chapter 7. Host-microbe Interactions in Drosophila Cancer.- Chapter 8. Drosophila as a Model for Metastasis.- Chapter 9. Epigenetic regulation in Drosophila Tumor Models.- Chapter 10. From the Making of a neural lineage to the Making of a Tumor: Lessons from the “simple” Drosophila Brain.- Chapter 11. Drosophila Melanogaster as a Model System for Human Glioblastoma.- Chapter 12. Translationally Controlled Tumor Protein (Tctp) and Growth Regulation in the Drosophila model.- Chapter 13. Modelling Cancer in Drosophila: Exploration to Personalised Medicine.- Chapter 14. SVC112; from hummingbirds to Head and Neck Cancer.\u003c\/p\u003e","brand":"Wu-Min Deng","offers":[{"title":"Default Title","offer_id":53651205783879,"sku":"9783031970351","price":245.03,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/the-drosophila-model-in-cancer-ebook-cover.webp?v=1775328501"},{"product_id":"substance-and-non-substance-addiction-ebook","title":"Substance and Non-substance Addiction","description":"\u003cp\u003eChapter 1. \u003cspan class=\"TextRun SCXW112974715 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW112974715 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eDefinition of Substance and Non-\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW112974715 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003esubstance\u003c\/span\u003e\u003cspan class=\"NormalTextRun SCXW112974715 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003e Addiction.- Chapter 2. \u003cspan class=\"TextRun SCXW244776756 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW244776756 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and differences in neurobiology.- Chapter 3. \u003cspan class=\"TextRun SCXW127720866 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW127720866 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and differences in genetics.- Chapter 4. \u003cspan class=\"TextRun SCXW224888915 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW224888915 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and differences in neuroimaging.- Chapter 5. \u003cspan class=\"TextRun SCXW21057113 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW21057113 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and differences\u003c\/span\u003e \u003cspan class=\"NormalTextRun SCXW21057113 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003ein psychology.- Chapter 6. \u003cspan class=\"TextRun SCXW59717350 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW59717350 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and Differences in Diagnostic Criteria.- Chapter 7. \u003cspan class=\"TextRun SCXW233360595 BCX8\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW233360595 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSimilarities and Differences in Diagnostic Scales.- Chapter 8. \u003cspan class=\"TextRun SCXW85583651 BCX8\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW85583651 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eBiochemical diagnosis in substance and non-substance addiction.- Chapter 9. \u003cspan class=\"TextRun SCXW168821700 BCX8\" lang=\"EN-IN\" xml:lang=\"EN-IN\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW168821700 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eDevelopment of New Diagnostic Techniques – Machine Learning.- Chapter 10. \u003cspan class=\"TextRun SCXW20464917 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW20464917 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eDrug Therapy.- Chapter 11. \u003cspan class=\"TextRun SCXW57011189 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW57011189 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003ePhysical Therapy for addiction.- Chapter 12. \u003cspan class=\"TextRun SCXW256103421 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW256103421 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eTraditional Chinese Medicine (TCM) Therapy.- Chapter 13. \u003cspan class=\"TextRun SCXW58881543 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW58881543 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eNutrition support therapy.- Chapter 14. \u003cspan class=\"TextRun SCXW13106249 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW13106249 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003ePsychotherapy.- Chapter 15. \u003cspan class=\"TextRun SCXW54632545 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW54632545 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eCognitive-Behavioral Therapy.- Chapter 16. \u003cspan class=\"TextRun SCXW42979374 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"\u003e\u003cspan class=\"NormalTextRun SCXW42979374 BCX8\" data-ccp-parastyle=\"No Spacing\"\u003eSummary and Prospect of Addiction.\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Xiaochu Zhang","offers":[{"title":"Default Title","offer_id":53651292750151,"sku":"9789819524112","price":192.59,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/substance-and-non-substance-addiction-ebook-cover.webp?v=1775332089"},{"product_id":"retinal-degenerative-diseases-xx-ebook","title":"Retinal Degenerative Diseases XX","description":"\u003cp\u003e\u003cstrong\u003ePart I: Age-Related Macular Degeneration (AMD)\u003c\/strong\u003e.- Associations of the adaptive immune system and age-related macular degeneration.- Macrophages and and age-related macular degeneration.- RPE basal lamina biology and pathophysiology related to age-related macular degeneration.- Genotype-Phenotype Correlations and Genetic Risk Assessment in Age-Related Macular Degeneration.- Photoreceptor degeneration: more than a bystander in age-related macular degeneration.- Cellular Senescence–an emerging player in the pathogenesis of AMD.- \u003cstrong\u003ePart II - Inherited Retinal Degenerations\u003c\/strong\u003e.- Novel Potentially Pathogenic Variants in TBC1D32 cause Non-syndromic Rod-Cone Degeneration.- The BXD32 Mouse: A High-Fidelity Model of Chronic Retinal Inflammation and Photoreceptor Degeneration.- The challenge of VUS in inherited retinal degeneration: insight from functional studies.- ABCA4 c.5461-6T\u0026gt;C causes Stargardt disease through exon skipping.- Assessment of ABCA4 Genetic Variants: Current Landscape and Future Prospects.- Exploring the Role of ABCA4’s ECD2 Domain in Inherited Retinal Degeneration: Computational and Functional Perspectives.- MFRP in early-onset retinal degeneration: Clinical and Molecular Perspectives.- Genetic Landscape of Non-syndromic Retinitis Pigmentosa in Portugal.- Part III: Gene Therapy and Gene Editing.- Frequency and Pattern of Gene Therapy Clinical Trials for Inherited Retinal Diseases.- CRISPR\/Cas-mediated gene activation as a versatile tool for treatment of inherited retinal dystrophies.- Prime Editing Strategy to Install the RPE65 c.1430A\u0026gt;G Dominant Mutation.- Megabase deletion of the human EYS locus using CRISPR\/Cas9.- Prime Editing Strategy to Install the Mfrp Retinal Degeneration 6 mutation.- Precise Gene Editing Technologies In Retinal Applications.- \u003cstrong\u003ePart IV: Immunity and Inflammation\u003c\/strong\u003e.- Current perspectives of TLR2 signalling in the retina.- Monocytes in Retinal Degeneration: Little Cells with a Big Impact.- Understanding the different microglia functional states to modulate their activity in retinal degeneration.- Progress in assessing retinal microglia using single-cell RNA sequencing.- The Role of Microglia in Glaucomatous Pathology.- \u003cstrong\u003ePart V: In-Vivo Imaging for Structure and Function\u003c\/strong\u003e.- Non-invasive assessment of ocular structure in the elderly 13-lined ground squirrel.- \u003cstrong\u003ePart VI: Mechanisms of Degeneration.-\u003c\/strong\u003e Potential Role of NUR77 in the Aging Retinal Pigment Epithelium and Age-Related Macular Degeneration.- Identification of unexpected pathomechanisms underlying the human Usher syndrome.- The loss of Usher II proteins in mice does not affect photoreceptor ultrastructure.- A role for SARM1 in photoreceptor cell death.- Exploring Histone Modifications in Inherited Retinal Disorders.- Effect of photobiomodulation on proliferative changes in the retina: Evidence from an in vitro model of PVR.- \u003cstrong\u003ePart VII: Mechanisms of Degeneration\u003c\/strong\u003e - Animal Models.- Calcium binding protein 4 is fundamental for retinal structure and function.- Association between C22:5-containing lipids and RPE Pathologies in Mice with Tmem135 Overexpression.- Extracellular Matrix Gene Expression Patterns in Retinal Wound Healing: A Comparative Study between Mouse and Zebrafish Laser Injury Models.- Zebrafish as a Model for Stargardt Disease.- Fish models of ageing retinal disease.- The power of zebrafish in disease modeling and therapy discovery for inherited retinal degeneration.- Unexpected retinal abnormalities in the cone-dominant northern tree shrew.- Deletion of Pnpla2 Causes Malformation and Malperformance of Mouse Photoreceptors.- Light as a mediator of acute and chronic retina degeneration.- A Knockin Model with the mouse equivalent to the c.2299delG Mutation in usherin Exhibits Early-Onset Hearing Loss and Progressive Retinal Degeneration.- Oxidative stress and energetic failure: common features and dissimilarities in 3 different mouse models of retinal pigment epithelium phagocytosis defects.- \u003cstrong\u003ePart VIII: Mechanisms of Degeneration – Metabolism\u003c\/strong\u003e.- The connection between cellular metabolism and retinal disease.- Stimulation of Thyroid Hormone Signaling Induces Stress Responses in Mouse Retina.- Ocular Tissue-Specific Amino Acid Metabolism in Gyrate Atrophy.- \u003cstrong\u003ePart IX: Neuroprotection\u003c\/strong\u003e.- Is Caveolin-1 required for retinal neuroprotection?.- Brain-derived neurotrophic factor in retinal integrity under diabetic and hypoxic conditions.- \u003cstrong\u003ePart X_  Photoreceptors\u003c\/strong\u003e.- Girdin is a Class I Phosphatidylinositol 3-kinase Binding Protein in the Retina.- Photoreceptor disc morphogenesis: who are the conductors of this highly metronomic process?.- Mechanism of photoreceptor outer segment tip ingestion: Evidence of trogocytosis.- The PRPH2 D2 Loop: Biochemical Insights and Implications in Disease.- Vulnerability of the Nrl−\/− Cone-Dominant Retina to Endoplasmic Reticulum Stress.- Molecular components of vesicle cycling at the rod photoreceptor ribbon synapse.- \u003cstrong\u003ePart XI: RPE\u003c\/strong\u003e.- Less is more: the RPE cell culture medium additive THT mildly impairs RPE health.- Desmosome and Hemidesmosome Disassembly in Retinal Pigmented Epithelium – Intersection with the Exosome Pathway.- Signaling pathways in Retinal Pigment Epithelium (RPE) cells in response to stress conditions of Age-Related Macular Degeneration (AMD).- The Importance of Differentiated RPE Cultures to Study Cell Biological Processes.- IGFBP5 as a Novel Basolateral Secretion Marker in the Retinal Pigment Epithelium.- Role of microsomal triglyceride transfer protein (MTP) in lipid processing pathways in retinal pigment epithelium.- Immunogenic switch of RPE cells.- Mitochondrial DNA Damage in the retinal pigmented epithelium (RPE) and its role in RPE pathobiology.- \u003cstrong\u003ePart XII: Stem Cell Models and Therapies\u003c\/strong\u003e.- Live imaging microscopy of human retina organoids: Photoreceptor pathology.- The Importance of Choriocapillaris Replacement in Therapeutic Strategies for Age-Related Macular Degeneration.- Classifying Mouse RPE Morphometric Heterogeneity Using REShAPE – an AI-based Image Analysis Tool.- Dysregulation of Retinal and Photoreceptor Structural Integrity Genes in ATF6-\/- Retinal Organoids.- Engineering specific human iPS reporter cell lines to generate optogenetically modified photoreceptors.- \u003cstrong\u003ePart XIII: Retinal Cell Biology\u003c\/strong\u003e.- Phosphoinositide 3-Kinase Enhancer Protein: Insights into its Expression and Functions in Retinal Cells.- Expression of Versican in the retina and its implication in retinal disease.- The role of RPE phagocytosis in the retina metabolic ecosystem.- Ocular Localization of Complement Factor H and its Association with Diseases in the Eye.- The Role of Primary Cilia in the Eye.- Key Claudins at the Blood-Retina Barriers.- NUDC is Critical for Mitosis and Postmitotic Cell Maintenance Through its Modulation of Dynein and Actin Cytoskeletal Reorganization.- Interplay of Retinal and Choroidal Vasculatures in Ocular Health and Disease.- Genetically encoded metabolic sensors to study retina metabolism.- Riboflavin, retbindin and riboflavin transporters in the retina.- Critical Roles of SEA Domains.- \u003cstrong\u003ePart XIV: Drug and Other Therapies\u003c\/strong\u003e.- Targeting connexins biology as therapeutic strategies against retinal diseases.- Uncovering Novel Drugs that Restore Vision Using Orthogonal Pooling in Zebrafish.- Steroid-Nitroxide Hybrid Compound Protects the Retina in a Model of CNV.- \u003cstrong\u003ePart XV: Human Studies\u003c\/strong\u003e.- Artificial Intelligence-assisted Matching of Human Postmortem Donors to Ocular Research Projects.- Late-Onset Retinal Degeneration: clinical features and C1QTNF5\/CTRP5 function.\u003c\/p\u003e","brand":"Catherine Bowes Rickman","offers":[{"title":"Default Title","offer_id":53651647168839,"sku":"9783031765506","price":373.43,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/retinal-degenerative-diseases-xx-ebook-cover.webp?v=1775337590"},{"product_id":"iron-metabolism-in-human-health-and-disease-ebook","title":"Iron Metabolism in Human Health and Disease","description":"\u003cp\u003eThis book provides a state-of-the-art overview on the role of bioiron in health and disease. Iron is an essential constituent of simple and complex organisms and has played a critical role in the origin of life. Cells utilize iron for energy metabolism, oxygen transport, and several biochemical reactions due to its flexible coordination chemistry and its unique ability to serve both as electron donor and acceptor. The term “bioiron” was coined to emphasize the importance of iron in biology and medicine.\u003c\/p\u003e\n\u003cp\u003eEven though iron is an abundant metal, its bioavailability is limiting. This often leads to iron-deficient states, which manifest in anemia and other co-morbidities. In fact, iron deficiency is the most common medical condition worldwide. On the other hand, excess iron is potentially toxic due to its redox reactivity. Iron toxicity is illustrated in pathologies of iron overload disorders, such as hereditary hemochromatosis or iron-loading anemias. Deregulation of iron metabolism is also observed in prevalent metabolic, cardiovascular, or neurological disorders.\u003c\/p\u003e\n\u003cp\u003eOur knowledge of iron metabolism has dramatically increased during the last 30-40 years with the discovery of elegant iron homeostatic networks that operate at the cellular and systemic levels. These include the IRE\/IRP regulatory system and the hepcidin\/ferroportin axis. The iron hormone hepcidin has emerged as a master regulator of systemic iron traffic and as a pharmacological target for iron-related disorders. \u003c\/p\u003e\n\u003cp\u003eThe book offers a comprehensive overview of the rapidly growing bioiron field and aims to attract the attention of students, basic scientists, and clinicians.\u003c\/p\u003e","brand":"Kostas Pantopoulos","offers":[{"title":"Default Title","offer_id":53652384678215,"sku":"9783031920332","price":234.33,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/iron-metabolism-in-human-health-and-disease-ebook-cover.webp?v=1775360402"},{"product_id":"innate-immunity-pattern-recognition-and-effector-mechanisms-ebook","title":"Innate Immunity: Pattern Recognition and Effector Mechanisms","description":"\u003cp\u003eThis contributed volume follows up and expands upon Target Pattern Recognition in Innate Immunity (2009), providing a much-needed update on an area that has surged to the forefront of medical research in recent years. From the initial idea of pattern recognition on microbial surfaces, innate immunity is now recognized as a key player in human health and disease, by virtue of its ability to regulate adaptive immune responses with important physiological and pathological consequences. This book presents cutting edge research and future perspectives on nearly all aspects of innate immunity. Coverage includes cells of the innate immune system, pattern recognition receptors and effector mechanisms, soluble PRRs and humoral factors, immune response to viral, bacterial, fungal, and parasitic pathogens, disease mechanisms, and comparative studies in non-mammalian innate immunity. 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A pilot neuroeducational study.- 29-Genes Classification Based on Multi Class SVMs with Systematic Sampling and Hierarchical Clustering (SSHC) Algorithm.- 30-Multinetwork motor learning as a model for dance in neurorehabilitation.- 31-Controlling the chimera form in the Leaky Integrate-and-Fire model.- 32-Qualitative differences between the Semi-separable and the “Almansi type” Stokes stream function expansions in the study of biological fluids.- 33-A multiscale mathematical model for tumor growth, incorporatingthe GLUT1 expression.\u003c\/p\u003e","brand":"Panagiotis Vlamos","offers":[{"title":"Default Title","offer_id":53652489666887,"sku":"9783032033949","price":298.53,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/genedis-2024-ebook-cover.webp?v=1775370029"},{"product_id":"genedis-2024-ebook-1","title":"GeNeDIS 2024","description":"\u003cp\u003e1-Attitudes and smoking prevalence among undergraduate students in central Greece.- 2-Care of patients with Alzheimer’s disease.- 3-Regulation of antioxidant enzymes levels in rat brain.- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy.- 5-Cerebral critical closing pressure at concomitant traumatic brain injury.- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias.- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates.- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases.- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma.- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study.- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients.- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial.- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents.- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study.- 15-Kisspeptin and the genetic obesity interactome.- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis.- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia.- 18-Ebola virus disease and current therapeutic strategies; 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Stacey","offers":[{"title":"Default Title","offer_id":53652946387271,"sku":"9783031972973","price":160.49,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/5455\/2903\/files\/cell-therapy-manufacturing-ebook-cover.webp?v=1775386809"},{"product_id":"cell-biology-and-translational-medicine-volume-24-ebook","title":"Cell Biology and Translational Medicine, Volume 24","description":"\u003cp\u003e\u003cspan style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-theme-font: minor-latin; mso-ansi-language: EN-IN; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\"\u003eThe Role of Mesenchymal Stem Cell-Derived Exosomes in Skin Regeneration, Tissue Repair, and the Regulation of Hair Follicle Growth.- \u003cspan lang=\"EN-CA\" style=\"font-size: 11.0pt; font-family: 'Calibri',sans-serif; 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